Mechanism of human rhinovirus infections

Mechanism of human rhinovirus infections

About 150 human rhinovirus serotypes are responsible for more than 50 % of recurrent upper respiratory infections. Despite having similar 3D structures, some bind members of the low-density lipoprotein receptor family, some ICAM-1, and some use CDHR3 for host cell infection. This is also reflected in the pathways exploited for cellular entry. We found that even rhinovirus serotypes binding the ...

New aspects on human rhinovirus infections.

1137Epidemiology and Persistence of Human Rhinovirus Infections in Childcare

Childcare Emily T. Martin, MPH, PhD; Hillary Jones; Emily Martin, BS; Helen Y. Chu, MD MPH; Mary Fairchok, MD; Jane Kuypers, PhD; Janet A. Englund, MD, FIDSA; Pharmacy Practice, Wayne State University, Detroit, MI; Seattle Children’s Hospital, Seattle, WA; Allergy and Infectious Diseases, University of Washington, Seattle, WA; Infectious Disease Clinical Research Program, Tacoma, WA; University...

Molecular Epidemiology of Human Rhinovirus Infections in Kilifi, Coastal Kenya

This study reports pediatric surveillance over 3 years for human rhinovirus (HRV) at the District Hospital of Kilifi, coastal Kenya. Nasopharyngeal samples were collected from children presenting at outpatient clinic with no signs of acute respiratory infection, or with signs of upper respiratory tract infection, and from children admitted to the hospital with lower respiratory tract infection....

Human Rhinovirus Infections in Rural Thailand: Epidemiological Evidence for Rhinovirus as Both Pathogen and Bystander

BACKGROUND We describe human rhinovirus (HRV) detections in SaKaeo province, Thailand. METHODS From September 1, 2003-August 31, 2005, we tested hospitalized patients with acute lower respiratory illness and outpatient controls without fever or respiratory symptoms for HRVs with polymerase chain reaction and molecularly-typed select HRVs. We compared HRV detection among hospitalized patients ...